Rubuphine® 10mg

Generic Name: Nalbuphine

Strength: 10 mg per ml

Dosage Form: Injection

Indication: Management of moderate to severe pain, adjunct for anesthesia, pain relief during labor and delivery​

Dosage

Administered by a qualified healthcare professional, not for self-administration.​

Dosage and frequency are determined by the healthcare provider based on the patient's condition and response.​

Storage

Store in a cool and dry place away from sunlight

Safety Information and Precautions

Contraindications: Do not use if allergic to Nalbuphine or any components of the injection. Avoid in patients with severe respiratory depression, acute or severe bronchial asthma, or known gastrointestinal obstruction.​

Respiratory Depression Risk: Monitor for signs of respiratory depression, especially upon initiation or following a dose increase.​

Central Nervous System Effects: May cause drowsiness or dizziness; avoid driving or operating heavy machinery until effects are known.​

Avoid Alcohol: Consuming alcohol can increase drowsiness and the risk of serious side effects.​

Use in Specific Populations: Exercise caution in patients with liver or kidney impairment, head injury, increased intracranial pressure, or a history of substance abuse.​

Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding.​

Side Effects

Common side effects may include:

Drowsiness​

Nausea​

Vomiting​

Dry mouth​

Constipation​

Sweating​

Injection site reactions (pain, redness, swelling)​

If any side effects persist or worsen, inform your healthcare provider promptly.​

Drug Interactions
Inform your doctor about all medications you are taking, as Rubuphine 10mg Injection may interact with:​

Other opioid analgesics​

Central nervous system depressants (e.g., benzodiazepines, muscle relaxants)​

Monoamine oxidase inhibitors (MAOIs)​

Anticholinergic drugs​

Rubuphine® 10mg Injection is effective in managing various pain-related conditions:​

Moderate to Severe Pain Relief: Alters pain perception, providing relief in conditions requiring opioid-level analgesia.​

Adjunct to Anesthesia: Enhances the effectiveness of anesthesia by providing additional pain control during surgical procedures.​

Labor Pain Management: Offers pain relief during labor and delivery without significantly affecting uterine contractions.

Is Rubuphine® 10mg Injection habit-forming?
Yes, it has the potential for abuse and dependence. Use exactly as prescribed by your healthcare provider.​

Can Rubuphine® 10mg Injection be used for headaches or migraines?
No, it is not indicated for the treatment of headaches or migraines. Consult your doctor for appropriate medications for these conditions.​

What should I do if I miss a dose?
As this medication is administered by a healthcare professional, missed doses are unlikely. However, inform your doctor if a dose is missed.​

Can I stop using Rubuphine® 10mg Injection abruptly?
Do not discontinue use suddenly without consulting your doctor, as this may lead to withdrawal symptoms.​

Where can I obtain Rubuphine® 10mg Injection?
This medication is available by prescription and should be administered by a qualified healthcare professional.